creutzfeldt-jacob disease: first biopsy proven case in iran

نویسندگان

hossein kalanie

چکیده

a biopsy diagnosed patient with creut7,{eldt-jacob diseaseis reportedin. iran. this 53~year-old hunte'r,esented  n may 1994 to mehr hospital with typica clinical manifestations of creunfeldi-jacob disease and died 4 months later. brain biopsy revealed severe neuronal loss, spongiosis and gliosis oj cerebral cortex. e;xposureofthis hunter to the brain tissue ofanimals may explain the route of transmission ofthe disorder.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Creutzfeldt-Jacob Disease: a case report

Creutzfeldt-Jacob disease is a rare, neurodegenerative disease caused by a prion protein. The patients are usually between 40 and 60 years old. Most of the patients die within one year after onset of the disease. A typical case is reported. It is pointed out that such a dramatic development can cause anxiety and a feeling of inadequacy for close relatives. To avoid adverse consequences, it is i...

متن کامل

Diffusion-Weighted MR Imaging in Biopsy-Proven Creutzfeldt-Jakob Disease

OBJECTIVE To compare conventional and diffusion-weighted MR imaging in terms of their depiction of the abnormalities occurring in Creutzfeldt-Jakob disease. MATERIALS AND METHODS We retrospectively analyzed the findings of conventional (T2-weighted and fluid-attenuated inversion recovery) and diffusion-weighted MR imaging in four patients with biopsy-proven Creutzfeldt-Jakob disease. The sign...

متن کامل

creutzfeldt-jacob disease: a case report.

creutzfeldt-jacob disease is a prion disease which has a wide range of clinical presentations. its diagnosis is not simple and clinical manifestation along with eeg, mr imaging findings and cerebrospinal fluid (csf) analysis should be considered for a definite diagnosis. a-50-year-old woman referred with cognitive impairment, myoclonic jerks, mutism and difficulty in swallowing to our clinic. e...

متن کامل

Case reports of two biopsy-proven patients with Creutzfeldt-Jakob disease in Singapore.

INTRODUCTION Creutzfeldt-Jakob disease (CJD) is the most common transmissible human subacute spongiform encephalopathy. There is limited literature on CJD in Southeast Asia. We describe the clinical course and diagnostic evaluation of 2 Singapore patients with biopsy-proven CJD. CLINICAL PICTURE Two patients presented with non-specific symptoms such as withdrawal, forgetfulness, asthenia, gid...

متن کامل

Creutzfeldt-Jacob disease presenting as severe depression: a case report

BACKGROUND An 81 year old female presented with altered mental status after new onset of severe depression and suicidal ideation with recent psychiatric hospitalization. CASE PRESENTATION Key clinical features included muscle rigidity, prominent startle reflex, and rapidly progressing cognitive decline. Initial working hypothesis was serotonin syndrome or neuroleptic malignant syndrome but co...

متن کامل

Creutzfeldt-Jacob Disease with psychiatric onset: a case report Malattia di Creutzfeldt-Jacob con presentazione psichiatrica: un caso clinico

Case report We describe the case of an elderly female patient who presented with psychotic symptoms in the absence of neurological signs and symptoms, and after systematic diagnostic evaluation eventually turned out to be a sporadic CJD case. Conclusions In clinical practice CJD should not be neglected as differential diagnosis in elderly patients with negative psychiatric history referring to ...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
acta medica iranica

جلد ۳۳، شماره ۱-۲، صفحات ۴۷-۵۱

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023